Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 16.06
Human Site: T987 Identified Species: 22.08
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 T987 E A V L G Q Y T E E P L S Q E
Chimpanzee Pan troglodytes XP_507923 1056 119132 T987 E A V L G Q Y T E E P L S Q E
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 N787 S Q E L R N F N Q E G T K L V
Dog Lupus familis XP_534964 1334 149091 S1268 E K S V L G H S I E E P V S Q
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 T983 R E A L E Q C T E E L V S P E
Rat Rattus norvegicus O55165 796 89797 H730 I F E M E F S H D Q E Q D P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 Q1131 D A T V C E D Q T K D S E G S
Frog Xenopus laevis P28025 1060 119314 N992 D E P P V A V N D S V I S E R
Zebra Danio Brachydanio rerio NP_775368 955 106984 R889 E M E A T L G R V E M Q T S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 S987 E H D V S M H S V Q E L S E T
Honey Bee Apis mellifera XP_623508 706 80766 F640 L D Q V D K F F T E D L Y R D
Nematode Worm Caenorhab. elegans P46873 699 78760 S633 D S E N L A N S Y F K P V K Q
Sea Urchin Strong. purpuratus P46872 699 78679 V633 N M R K Q T P V A D K D K S L
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 S989 F A E L L H P S N K Q V D E P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 I974 E S L R A M P I E T L V E E F
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 S1037 N F P L S Q F S P K T P V P V
Red Bread Mold Neurospora crassa P48467 928 102392 E862 A A V K D R L E A A K A G S T
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 13.3 13.3 N.A. 46.6 0 N.A. N.A. 6.6 6.6 13.3 N.A. 20 13.3 0 0
P-Site Similarity: 100 100 26.6 40 N.A. 53.3 20 N.A. N.A. 33.3 33.3 26.6 N.A. 53.3 46.6 33.3 6.6
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 13.3 N.A. N.A. 13.3 13.3 13.3
P-Site Similarity: 40 N.A. N.A. 40 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 30 6 6 6 12 0 0 12 6 0 6 0 0 0 % A
% Cys: 0 0 0 0 6 0 6 0 0 0 0 0 0 0 0 % C
% Asp: 18 6 6 0 12 0 6 0 12 6 12 6 12 0 6 % D
% Glu: 36 12 30 0 12 6 0 6 24 42 18 0 12 24 18 % E
% Phe: 6 12 0 0 0 6 18 6 0 6 0 0 0 0 6 % F
% Gly: 0 0 0 0 12 6 6 0 0 0 6 0 6 6 0 % G
% His: 0 6 0 0 0 6 12 6 0 0 0 0 0 0 0 % H
% Ile: 6 0 0 0 0 0 0 6 6 0 0 6 0 0 0 % I
% Lys: 0 6 0 12 0 6 0 0 0 18 18 0 12 6 6 % K
% Leu: 6 0 6 36 18 6 6 0 0 0 12 24 0 6 6 % L
% Met: 0 12 0 6 0 12 0 0 0 0 6 0 0 0 0 % M
% Asn: 12 0 0 6 0 6 6 12 6 0 0 0 0 0 0 % N
% Pro: 0 0 12 6 0 0 18 0 6 0 12 18 0 18 6 % P
% Gln: 0 6 6 0 6 24 0 6 6 12 6 12 0 12 12 % Q
% Arg: 6 0 6 6 6 6 0 6 0 0 0 0 0 6 12 % R
% Ser: 6 12 6 0 12 0 6 30 0 6 0 6 30 24 6 % S
% Thr: 0 0 6 0 6 6 0 18 12 6 6 6 6 0 12 % T
% Val: 0 0 18 24 6 0 6 6 12 0 6 18 18 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 6 0 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _